2022 MLB Picks: Best Bets to Win American and National League Championships

2022 MLB Picks: Best Bets to Win American and National League Championships

Check out our best bets to win the 2022 MLB American and National League Championships.


While the Atlanta Braves are free to bask in their 2021 World Series victory, it's already time for us to start thinking about betting on MLB for the 2022 season. And since we've already tackled our way-too-early 2022 World Series picks, it only feels right that our next batch of 2022 MLB picks hit the best bets to win the American and National League Championships.

Of course, this early into the MLB offseason, the best online sportsbooks have yet to drop their 2022 MLB pennant race betting odds. But we can identify the top AL and NL contenders by taking stock of the opening 2022 World Series betting odds from BetOnline

Los Angeles Dodgers+550
Houston Astros+700
Chicago White Sox+1000
Toronto Blue Jays+1200
New York Yankees+1200
Atlanta Braves+1400
San Francisco Giants+1400
San Diego Padres+1400
Tampa Bay Rays+1400
Milwaukee Brewers+1400
Boston Red Sox+1800
St. Louis Cardinals+1800
New York Mets+2000
Philadelphia Phillies+2500
Cincinnati Reds+3000
Los Angeles Angels+4000
Seattle Mariners+4000
Oakland Athletics+5000
Detroit Tigers+5000
Detroit Tigers+7000
Cleveland Guardians+7000
Kansas City Royals+7000
Colorado Rockies+7000
Chicago Cubs+10000
Miami Marlins+10000
Washington Nationals+10000
Arizona Diamondbacks+25000
Texas Rangers+50000
Pittsburgh Pirates+50000
Baltimore Orioles+50000

Definitely check back to see when 2022 MLB World Series odds get officially released. For the time being, we will give you our three best 2022 MLB bets for the AL Championship and our three best 2022 MLB bets for the NL Championship. This way, you'll be ready to make a decision when 2022 MLB odds are fully announced later in the offseason.

2022 MLB Pennant Race Predictions

Before digging into our 2022 MLB AL and NL picks, please remember that analyzing next year's landscape is a difficult task at the moment. We have yet to see MLB go through the offseason. There will be trades, free-agency signings and even injuries that shake up rosters and impact the competitive field.

All of our current best 2022 MLB bets are based on rosters as they currently stand and try to account for any uncertainty or prospective moves that might be made. It's important to keep track of MLB offseason odds, though, so you can see if any of these teams suddenly become less-than-stellar wagers.

Better American League Bet: Houston Astros or Chicago White Sox?


Don't be one of those people who decides to write off the Houston Astros after their latest World Series loss. They might be 0-3 during their three championship-round appearances, but they have been one of the most dominant teams, if not the absolute most dominant, over the past half-decade.

Some people will talk themselves into the Chicago White Sox as the better American League bet. You shouldn't be one of them.

Houston Astros To win the 2022 American League Championship

Will the New York Yankees be Real AL Championship Contenders?


The short answer: Yes, we believe the New York Yankees will be in the thick of the 2022 AL pennant race

Indeed, they were super inconsistent this past season. But their offense started to show signs of life later in the year. A batting order with Aaron Judge and Giancarlos Stanton won't post a below-average slugging percentage again.

New York Yankees To win the 2022 American League Championship

The Toronto Blue Jays Could be AL Favorites


If push comes to shove, we're picking the Astros to come out of the American League next season. But we're giving real consideration to the Toronto Blue Jays.

Last year's squad led the league in slugging percentage and was second in batting average. Without a ton of key free agents, plus an average age of under 27 in their batting order, we're fully confident the Blue Jays will be back—and better than ever.

Toronto Blue Jays To win the 2022 American League Championship

Better National League Bet: San Francisco Giants or San Diego Padres?


Many will immediately side with the San Francisco Giants in this discussion. We're in the minority.

The Giants had a great year. They were probably the third best team in the regular season. But their offense is on the older side, and many of their best pitchers will be on the wrong side of 30 next year. 

The Padres are younger, and they have two potential MVP candidates in Manny Machado and Fernando Tatis Jr. Sure, they're coming off a crummy season. But they have plenty of room for internal improvement. 

San Diego Padres To win the 2022 National League Championship

Will the Reigning Champion Braves be NL Contenders?


Believe it or not, the Braves are barely laying top-seven World Series odds in 2022 after just winning the whole thing. That is incredibly weird.

Linemakers are likely accounting for the fact Atlanta didn't climb above .500 until mid-August this season. We don't care. They made a bunch of star acquisitions at the deadline, have money to spend this summer and are only at risk of losing one top-25 free agency. Consider them an NL championship contender until they prove to be the inverse.

Atlanta Braves To win the 2022 National League Championship

NL Beware: Dodgers Aren't Going Anywhere

Will the Los Angeles Dodgers be our top 2022 National League Championship pick? We're not yet sure. But to believe they're done contending is a joke.

No pitching staff posted a better ERA this season, and the average age of Los Angeles' arms remains under 29. Though the Dodgers have a cabal of really good players entering free agency, it's hard to worry about them taking a step back. They've shown in the past they'll pay to not only keep incumbent players, but acquire additional talent.

Los Angeles Dodgers To win the 2022 National League Championship

Check out this list of the best online sportsbooks so you can decide which one to use for all your MLB futures betting:

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