Jannik Sinner to follow up Wimbledon victory with 2025 US Open championship

What: 2025 Men's US Open Tennis Championships
Where: Flushing Meadows, Queens, New York City
When: August 24- September 7, 2025

Jannik Sinner ended his five-match losing streak to Carlos Alcaraz, becoming the first Italian player to win a Wimbledon singles title. Having already captured two of the year's three Grand Slams, the 23-year-old is the early US Open favorite.

Let's look at the latest betting lines for the event, which takes place in New York City later this summer. Odds are subject to change.

Outright
Jannik Sinner	+165	+165	+165
Carlos Alcaraz	+200	+200	+200
Novak Djokovic	+400	+400	+400
Alexander Zverev	+900	+900	+900
Jack Draper	+1200	+1200	+1200
Daniil Medvedev	+1400	+1400	+1400
Ben Shelton	+2500	+2500	+2500
Joao Fonseca	+2500	+2500	+2500
Taylor Fritz	+2500	+2500	+2500
Frances Tiafoe	+4000	+4000	+4000
Holger Rune	+4000	+4000	+4000
Stefanos Tsitsipas	+4000	+4000	+4000
Andrey Rublev	+5000	+5000	+5000
Casper Ruud	+5000	+5000	+5000
Jakub Mensik	+5000	+5000	+5000

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Sinner favored following Wimbledon win

Jannik Sinner is a +165 favorite to repeat as US Open champion. The 23-year-old Italian defeated Taylor Fritz in straight sets to win in Flushing Meadows in 2024. He followed that up with his second-consecutive Australian Open title earlier this year.

Heading into the final major of the season, Sinner has won the last three Grand Slam championships played on hard court.

Last 7 Grand Slams:
🏆Wimbledon 2025 - Sinner
🏆Roland Garros 2025 - Alcaraz
🏆Australian Open 2025 - Sinner
🏆US Open 2024 - Sinner
🏆Wimbledon 2024 - Alcaraz
🏆Roland Garros 2024 - Alcaraz
🏆Australian Open 2024 - Sinner

Who will win more? 🔥 pic.twitter.com/0AjTCjYEe3

— Emilio Sansolini (@EmilioSansolini) July 13, 2025

Can Alcaraz rebound?

Jannik Sinner squandered three championship points against Carlos Alcaraz (+200) at Roland Garros. The comeback victory gave the 22-year-old Spaniard his fifth major title and the upper hand on his "Big Two" rival.

Heading into Wimbledon, Alcaraz had won the past five head-to-head matches against Sinner. However, his 4-6, 6-4, 6-4, 6-4 defeat against the world No. 1 ended his 20-match winning streak at the All England Club. It also put a stop to Alcaraz's career-long 24-match unbeaten streak.

Alcaraz was 5-0 in major finals before losing to Sinner. How will he rebound from his first Grand Slam final loss?

Top contenders outside the Big Two

Novak Djokovic (+400) lost to Sinner in straight sets in the Wimbledon semi-finals. Chasing a record-extending 25th major, the 38-year-old has now made final-four exits at all three 2025 Grand Slams. He picked up his fourth US Open title in 2023.

Ben Shelton (+2500) suffered a straight-sets defeat to Sinner in the Wimbledon quarterfinals - his sixth-consecutive loss to the Italian. However, if he can somehow avoid Sinner in New York City, the 22-year-old could become the first American to win the tournament since Andy Roddick in 2023. He's now made at least the quarter-finals at three of the four majors.

It's a maiden #Wimbledon final for Jannik Sinner 💥

The Italian defeats Novak Djokovic with a dazzling 6-3, 6-3, 6-4 victory to line up a Sunday afternoon meeting with Carlos Alcaraz 🤝

Just world No.1 doing world No.1 things 😅 pic.twitter.com/jObVzUdMqA

— Wimbledon (@Wimbledon) July 11, 2025

2025 Men's US Open Championship Picks

While it's way more fun to pick longshots, betting on anyone but Sinner or Alcaraz seems like throwing your money away these days as the pair has captured the last seven majors.

We like Sinner (+165) to repeat as US Open champion and pull even with his rival with his fifth-career Grand Slam.

Jannik Sinner to win 2025 US Open

+165

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