Oklahoma State vs Kansas Picks

The Jayhawks' eight-game winning streak came to a screeching halt with a 74-56 loss at Iowa State on Saturday. Kansas will look to rebound on the road against an Oklahoma State team that's dropped three in a row.

Can Bill Self's club defeat the Cowboys in Stillwater on Wednesday night? Let's check the latest betting lines. Odds are subject to change.

	Spread	Money Line	Total Points
Kansas	-6.5 (-110)	-110	Ov 155 (-115)
Oklahoma State	+6.5 (-110)	-110	Un 155 (-105)

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Jayhawks favored on the road

Kansas is a 6.5-point road favorite on Wednesday night. The Jayhawks have won the last eight meetings versus Oklahoma St., including the last three in Stillwater. But this will be their first road matchup with the Cowboys since Steve Lutz took over at head coach.

KU is coming off an ugly 18-point loss to No. 5 Iowa State on Saturday, shooting just 37.3% for the game with 13 turnovers. However, on the bright side, Bill Self's club is 137-24 (85.1%) all-time following a loss, and 5-0 this season.

Kansas vs Houston next week on Big Monday.

-Big 12 title implications

-Bill Self’s 40-0 record at home on Big Monday with another test.

Buckle up folks pic.twitter.com/4id6Y5m7pQ

— Aint No Seats Podcast (@AintNoSeatsPod) February 17, 2026

Cowboys shooting blanks

Oklahoma State started the campaign strong with nine consecutive wins against non-conference opponents such as Texas A&M and Northwestern. Additionally, Steve Lutz's squad has impressive victories over UCF and BYU, but they've struggled versus Big 12 opponents, losing to both Baylor and Arizona State. No one surrenders more points per game (84.6) in Big 12 action than the Cowboys.

Anthony Roy leads OSU with 17.6 points per game thanks to a sparkling 42.2% conversion rate from three-point range. Parsa Fallah is also averaging 15.4 PPG and 6.2 RPG against conference opponents.

Kansas goes in for the kill

Wednesday's meeting will mark the first time the Cowboys and Jayhawks square off in conference play this year. Kansas is 9-3 against Big 12 opponents compared to the Cowboys' 4-8 conference record. Bill Self is also 9-8 all-time in Stillwater, with three-straight wins.

Darryn Peterson is pacing the Jayhawks with 19.8 PPG, scoring 20 or more points six different times this season. The star freshman guard is complemented by sophomore center Flory Bidunga, who is averaging 14.8 PPG with a team-leading 9.1 rebounds and 2.5 blocks.

Darryn Peterson iso work pic.twitter.com/WftlodRtuZ

— MBB Performances (@mbbperformances) February 14, 2026

Defense will be key for Kansas as they're limiting opponents to a 38.5% field goal percentage - tops in the Big 12 and fifth nationally. Bidunga and the Jayhawks should also dominate inside the paint as the Cowboys have struggled with rim protection and rebounding all season.

We'll take the Kansas to cover the -6.5 spread with the UNDER 155.

Kansas Jayhawks to cover vs Ok. State