• What: MLS  Cup Picks
  • When: Regular Season gets underway Saturday, February 21, 2026
  • Where: Soccer stadiums throughout the USA and Canada
  • Watch: Apple TV, FOX, FS1

It may not be about how the West was won in the MLS Cup odds, but it would certainly appear to be a case of expectations that the Cup will be won by a team from out West.

While it's true that reigning champions Inter Miami are the +400 betting choice to retain the title, the next three clubs in the MLS Cup betting line are all West Coast squads.

Los Angeles FC is the second betting choice at +550. They are followed in the MLS betting lines by the Vancouver Whitecaps (+900) and San Diego FC (+1200).

Let's take a look at the latest MLS Cup odds from the leading online sportsbooks. Remember, odds are always subject to change.

MLS Cup OddsBovadaBetUSBetOnline
Inter Miami+400+400+400
Los Angeles FC+550+550+550
Vancouver Whitecaps+900+900+900
San Diego FC+1200+1200+1200
FC Cincinnati+1400+1400+1400
Philadelphia Union+1400+1400+1400
Columbus Crew+1600+1600+1600
Los Angeles Galaxy+1600+1600+1600
New York City FC+1600+1600+1600
Seattle Sounders+1800+1800+1200
Orlando City+2500+2500+2500
Nashville FC+2500+2500+2500
New York Red Bulls+2800+2800+2800

FC Cincinnati (+1400), the Philadelphia Union (+1400), Columbus Crew (+1600), LA Galaxy (+1600), New York City FC (+1600) and Seattle Sounders (+1800) are all given odds to win the MLS Cup shorter than +2000.

Best MLS Cup Betting Tips

If you're new to betting on soccer, not to worry. Our soccer betting page is chock full of the best wagering advice and handy betting tips. Should you want to analyze data from the best MLS betting sites, with expert tips and wagering knowledge, it's easily accessible.

The MLS Cup is a season-ending competition, and the odds will fluctuate throughout the MLS season. Bookmark our MLS Cup final page to track the latest betting trends.

MLS Cup Format

The MLS Cup final is a single-knockout format. It's a one-and-done opportunity to win the title.

There have been five different MLS Cup winners over the past five years. Toronto FC in 2017 is the only Canadian side to have won the title.

MLS Cup Betting Picks

You have to go back to 2011-12, when David Beckham led the Los Angeles Galaxy to consecutive wins, to find a season in which a team successfully defended its MLS Cup crown.

Los Angeles FC (2022, 2023) was the most recent club to play in successive MLS Cup final matches.

Inter Miami (+400)

Start with two-time MLS MVP Lionel Messi, and really, do you need to go any further? Well, Inter Miami actually is adding depth to the club's championship-winning roster.

https://twitter.com/GBarca_/status/2020374718780444817

They must retool following the retirements of Jordi Alba and Sergio Busquets. And Inter Miami's back four doesn't exactly play air-tight defense.

Los Angeles FC (+550)

Son Heung-min and Denis Bouanga provide a dynamic striking partnership. The recent addition of Canadian international midfielder Stephen Eustáquio further bolsters the squad.

https://twitter.com/mari_mavi5/status/2020695412785782826

A key will be how quickly the club adapts to the tactics of new coach Marc Dos Santos, promoted from his role as an assistant coach of the staff.

Vancouver Whitecaps (+900)

A full season with Thomas Muller's scoring touch might be just enough to push Vancouver up a notch from losing finalists to champions.

San Diego FC (+1200)

Coach Mike Varas preaches a team-first concept. You can always count on San Diego FC to be right in there competing for the spoils.

FC Cincinnati (+1400)

Statistically, there's nothing flashy about the way FC Cincinnati plays. Yet you look at the MLS standings, and each week the club keeps on accumulating points and remaining in the hunt.

Philadelphia Union (+1400)

Union might be the perfect nickname for this club. They might not have any world-class superstars, but Philly is a picture of reliability, discipline, and consistency year in and year out.

Who Will the MLS Conference Winners Be?

In the future book wagering on MLS conference winners, Inter Miami is given the shortest betting line at +120 to win the Eastern Conference title. The Philadelphia Union is a distant second choice in this betting market at a line of +700.

After that, it gets tighter. FC Cincinnati (+800), New York City FC (+900), and the Columbus Crew (+1000) are all set with betting odds of +1000 or shorter.

Over in the Western Conference, oddsmakers aren't backing one team as solidly as they are rolling with Inter Miami in the East. Los Angeles FC (+275), the Vancouver Whitecaps (+400), and San Diego FC (+550) are all close contenders to finish atop the Western Conference.

Behind them, you'll also be able to access an MLS betting line shorter than +1000 on both the Los Angeles Galaxy (+700) and Seattle Sounders (+800).

Check Out These MLS Prop Bets

Inter Miami are given +200 favorite odds to reach the MLS Cup final for the second straight season. Next in the MLS prop wager is Los Angeles FC at a betting line of +275.

Finalists a year ago, the Vancouver Whitecaps are the third choice in this betting market at odds of +450

Best Bet To Win The MLS Cup Final

As much as it would be easy to simply roll with Messi and an Inter Miami repeat, history tells us long-term success stories are a rarity in MLS play. That's why we're going to look beyond the chalk to line up a winner.

Los Angeles FC To win MLS Cup
Bovada
+550
Bet Now!

Los Angeles FC won the title in 2022 and was the losing finalist in 2023. This will be the first full season of the Son-Bouanga striking partnership, while the addition of Eustáquio bolsters the midfield. Go with LAFC in the MLS Cup picks.