• What:  Japanese Grand Prix MotoGP Picks
  • Where: Mobility Resort Motegi
  • When: September 28, 2025
  • Watch: FOX Sports, 1 am EST

As the MotoGP riders head into Round 17 of the series at the Japanese Grand Prix, it's difficult to recall the last race that wasn't won by a member of the Marquez family.

The Marquez win streak is at nine races. Eight of those races were won by Marc Marquez. His little brother, Alex Marquez, posted one win during this span.

This week, it's once again Marc Marquez who oddsmakers are setting as the prohibitive -250 odds-on favorite.

Let’s look at the latest Japanese Grand Prix MotoGP betting lines. Remember, odds are always subject to change.

MotoGP Japan Grand Prix OddsBovadaBetOnlineBetUS
Marc Marquez-250-250-250
Alex Marquez+450+450+500
Marco Bezzecchi+800+800+800
Francesco Bagnaia+900+900+1000
Pedro Acosta+1800+1600+1400
Fabio Quartararo+2200+2500+2200
Fabio Di Giannantonio+3300+4000+4000
Franco Morbidelli+3300+4000+4000
Brad Binder+5000+5000+6600
Enea Bastianini+6000+5000+5000
Fermin Aldeguer+6000+5000+6600
Luca Marini+6000+5000+6600
Jorge Martin+6600+5000+6600
Maverick Vinales+6600+6600+6600

Marc’s younger brother is the second betting choice at +450. Marco Bezzecchi is next, with a MotoGP betting line of +800. Two-time world champion Francesco Bagnaia is set at +900.

Pedro Acosta (+1800) and Fabio Quartararo (+2200) are the only other riders with odds shorter than +3300.

Marc Marquez Can Clinch MotoGP Title In Japan

Marc Marquez leads the MotoGP standings by 182 points. If he increases that margin to 185 points by the end of this race weekend, he'll clinch the series title.

He is a three-time champion in the Japanese Grand Prix. However, this race has seen four different winners over the past four races.

In this season’s race, following Saturday's qualifying will be the 12-lap sprint. The 24-lap main event race is set for Sunday at 1 a.m. EST around the 14-turn, 2.983-mile Mobility Resort Motegi layout. Remember, the race odds could be changing based on the results of the qualifying round and the sprint race. That’s why it’s always wise to track the early outcomes. You’ll be able to see which riders are holding hot hands and are the best for you to bet.

Let's look at the top contenders for this race.

Marc Marquez (-250)

The six-time world champion shows a record of five victories in Japan. Marc Marquez is a three-time winner of the MotoGP Japanese Grand Prix in 2016, 2018, and 2019. He also won once in Moto2 (2012) and once in 125cc (2010).

He's finished on the podium in 10 successive MotoGP races.

Alex Marquez (+450)

The younger member of the Marquez family has won three titles in Japan, albeit none of them in the MotoGP class. Alex Marquez won once in Moto2 (2017) and twice in Moto3 (2013, 2014).

His best finish in Japan in MotoGP was a seventh-place performance last year.

Marco Bezzecchi (+800)

Bezzecchi continues to be the best non-Marquez story of the MotoGP season. He's finished on the podium in five of the past seven races.

A win by the Aprilia rider in the Great Britain GP was the last victory in the series by a rider not named Marquez. He's started on the pole in two of the past four races.

Francesco Bagnaia (+900)

Bagnaia is the reigning champion in this race. He also won in Japan in the Moto2 class in 2018.

However, Bagnaia has gone five races in a row without a podium finish.

Pedro Acosta (+1800)

The Spanish rider has shown four finishes in the top four over the past five races. That includes a pair of podium performances.

Fabio Quartararo (+2200)

Quartararo has gone 11 consecutive races without a podium placing since his second-place showing in the Spanish Grand Prix.

Latest MotoGP Championship Odds

In MotoGP futures, so far ahead of the pack are the Marquez brothers that oddsmakers are opting to eliminate them from championship betting. Bookmakers are now offering a betting line on the MotoGP world title minus Marc and Alex Marquez.

In these new MotoGP odds, Bezzecchi is the -175 odds-on pick to finish third overall in the season standings. Bagnaia is set with a betting line of +175.

After that, the best bets are Acosta at +2200, followed by Fabio Di Giannantonio and Franco Morbidelli, each with MotoGP betting lines of +2500.

Japanese Grand Prix MotoGP Best Bet

Among the recent winners of this race, none of Bagnaia (2024), Jorge Martin (2023), or Jack Miller (2022) are running at all well this season.

Marc Marquez To win MotoGP Japanese Grand Prix
Bovada
-250
Bet Now!

Marc Marquez, meanwhile, is on top of his game. And he is sitting on the best equipment on the circuit. That is continuing to be a winning package. Stay with the hot hand. Bet Marc Marquez to win in the MotoGP Japanese Grand Prix picks.

Additional Thoughts And Notes Regarding MotoGP Bets

Once you are all up to speed on the latest MotoGP Japan Grand Prix news and information, make sure to check out the fantastic array of resources for you over at OSB. Of course, for even more analysis on the topic covered here, you should bookmark the MotoGP betting sites rundown. On this page, you can find a variety of awesome information as it relates to the sport, including the latest betting markets and beyond. Additionally, for those on the go, another fantastic page to familiarize yourself with is the best betting apps breakdown, which goes over all of the nuances of mobile betting sites and beyond. Finally, for those interested in maximizing their wagers, look no further than the best betting sites guide, which contains an extensive compilation of tips and how-to suggestions.