Cowboys vs Chiefs Picks | 11-27-25 | Online Sports Betting

What: Kansas City Chiefs at Dallas Cowboys
Where: AT&T Stadium in Arlington, TX
When: 4:30 PM EST, Thursday, November 27th, 2025

The Cowboys will host the Chiefs on Thanksgiving Day after both teams orchestrated season-saving comeback wins on Sunday. Dallas climbed out of an early 21-0 hole to defeat the division-rival Eagles while Kansas City secured their first one-score victory of the year with a 23-20 OT win over Indianapolis.

Let's look at the latest betting lines for Thursday's game. Odds are subject to change.

	Spread	Money Line	Total Points
Kansas City Chiefs	-3.0 (-115)	-165	Ov 52.0 (-110)
Dallas Cowboys	+3.0 (-105)	+140	Un 52.0 (-110)

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Chiefs favored in Arlington

Kansas City is a 3-point road favorite at AT&T Stadium on Sunday. Down 20-9 to the Colts in the fourth quarter, Patrick Mahomes and the Chiefs scored on three of their final four drives to steal a much-needed 23-20 OT victory. Rashee Rice made two crucial catches down the stretch, finishing with 111 yards on four receptions, and Kareem Hunt ran for 104 yards and a TD on 30 carries.

The victory over Indianapolis was Andy Reid's club's first one-score W of the season after winning 11 such games in 2024 and losing all five one-score contests this year.

Patrick Mahomes becomes the fastest player in NFL history to reach 35,000 career pass yards 🫡@Chiefs | #ChiefsKingdom pic.twitter.com/H2inhMy9Ev

— NFL+ (@NFLPlus) November 23, 2025

Dallas stuns the Eagles

The OVER/UNDER for Thursday's Thanksgiving Day contest is 52 points. The Cowboys' offense is averaging the fourth-most points per game (29.1) in the NFL under first-year head coach Brian Schottenheimer. With nine receptions for 146 yards and a TD, George Pickens was essential to his team's 21-point comeback win over Philadelphia in Week 12.

Pickens wasn't the only Jerry Jones acquisition that paid off on Sunday. Former New York Jet Quinnen Williams had eight QB pressures and a tackle for loss. Dallas is 5-5-1 following back-to-back victories but needs a home win over KC to stay alive in the NFC playoff race.

Run defense shines on both sides

Javonte Williams will have his hands full with a Steve Spagnuolo defense that limited Jonathan Taylor to 58 yards on 16 carries. After scoring nine TDs in his first eight games this season, the Cowboys veteran back is scoreless in the last three contests.

Meanwhile, Dallas' defense stuffed Saquon Barkley for 22 yards on 10 attempts. After permitting three TDs on the Eagles' first three possessions, they held them scoreless the rest of the game.

Dak Prescott is now the Cowboys’ all-time passing leader, surpassing Tony Romo 😤

History made. pic.twitter.com/McXkRdcNsR

— ESPN (@espn) November 23, 2025

Dallas Cowboys vs Kansas City Chiefs Picks

Both teams are in desperate need of a win on Thanksgiving to keep their playoff hopes alive. With most expecting the Chiefs to come out on top and make another run at the Super Bowl, we'll go the other way and lock in the Cowboys (+140) at home with the OVER 52.

Dallas Cowboys to win vs Chiefs

+140

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