NFL Betting News This Month | Latest Super Bowl Line Movement, Market Watch & CPOY Favorites | September 23, 2026
Two weeks into the NFL regular season, four starting quarterbacks are already out of action. For three of the teams, it’s an outcome that’s proving devastating to their Super Bowl betting lines.
For the reigning Super Bowl champion Seattle Seahawks, it’s been business as usual.
The Seahawks lost QB1 Sam Darnold to a glute injury in the first quarter of their Week 1 win over the New England Patriots in a rematch of last season’s Super Bowl. In stepped backup Drew Lock, and the Seahawks haven’t missed a beat. They are 2-0.
Jayden Daniels was carted off vs. the Cowboys after going down with an apparent elbow injury.
Daniels tried to hold himself up as he was falling down and his elbow bent in an awkward way.
(📺 FOX) pic.twitter.com/dcTQLDgKws
— SportsCenter (@SportsCenter) September 20, 2026
The Chicago Bears stumbled to a Week 2 loss to Minnesota after Caleb Williams was lost to a hamstring injury. Meanwhile, the Washington Commanders saw QB1 Jayden Daniels suffer a painful-looking elbow injury. And on Monday Night Football, as they lost to the Rams, the New York Giants also lost QB Jaxson Dart to a knee injury.
Even bouncing back from their Week 1 loss to the San Francisco 49ers, the Rams’ Super Bowl odds lengthened from +600 to +675. Yet the Rams remain the chalk to win the big game.
Futures markets are now reacting to roster moves, quarterback health, rest advantages, and Week 2 outcomes. For all your news, views, and analysis, check out NFL betting.
Biggest NFL betting storylines this month
Chiefs' outstanding Pat
Bears crumble without Williams
49ers looking Purdy
Chalk holding serve
NFL ATS best bets
Two weeks into the season, there are just seven NFL teams left that are a perfect 2-0 against the spread. Interestingly, only one of those seven teams posted a winning ATS mark last season.
The San Francisco 49ers have picked up where they left off. They were 11-7-1 ATS last season, fifth-best in the NFL.
However, it's a whole new world for San Francisco's six compatriots who are also 2-0 ATS this season. The Las Vegas Raiders were 7-10 ATS last season and the New York Jets were 7-9-1. Among the other 2-0 ATS clubs, none of the New Orleans (9-8), Cincinnati Bengals (8-9), Minnesota Vikings (8-9), or Buffalo Bills (9-10) were reliable ATS bets last season.
Who to bet over and who to bet under
In two games this season, both the Detroit Lions and Buffalo Bills have scored 30 or more points and allowed 30 or more points. As they met in Week 2, there might not be a better over bet for the rest of the 2026 NFL season. Even though the total on the game was set at a whopping 72 points, the two teams easily hit the over as Buffalo beat Detroit 41-31.
The Bills and Lions are among seven NFL teams that are 2-0 on the total this season. Others on this list include the Tampa Bay Buccaneers, Philadelphia Eagles, Washington Commanders, Cleveland Browns, and Indianapolis Colts.
Eight teams are 0-2 on the total so far this season, meaning they've gone under in both games. That group includes the New York Jets, Las Vegas Raiders, New England Patriots, Seattle Seahawks, Pittsburgh Steelers, Denver Broncos, Atlanta Falcons, and Los Angeles Chargers.
Super Bowl odds movers: biggest risers, fallers and value bets
Biggest risers
Buffalo Bills (+750)
Putting up 41 points on the Lions, the Bills celebrated a successful launch of the new Highmark Stadium. The Bills are the AFC team with the shortest betting line to win the Super Bowl. Buffalo's Super Bowl odds shortened from +900 to +750.
Bills QB Josh Allen, the +250 favorite in NFL MVP futures, can beat teams with his feet or his arm. He averaged a career-best 9.7 yards per attempt in the win over Detroit. Allen already has three TD passes of 20+ yards this season.
San Francisco 49ers (+1200)
For the second week in a row, the Super Bowl futures market on the 49ers shortened. They were at +1400 to win the big game following their Week 1 dismantling of the Rams.
Fifth-year QB Purdy is being touted as an NFL MVP candidate. His 94.9 QB rating leads the league. The Niners this week added veteran WR Brandin Cooks to the practice roster following an injury to starting WR Mike Evans.
Kansas City Chiefs (+1200)
The 10-2 OT record of KC's Patrick Mahomes is the best of any QB in NFL history with at least 10 OT starts. He's a perfect 8-0 in regular-season OT. Mahomes is the overwhelming -250 chalk to be the NFL's Comeback Player of the Year. KC, meanwhile, has shortened from +1600 to +1200 to win the Super Bowl.
The Chiefs are a double threat on offense thanks to the presence of RB Kenneth Walker III. He accumulated 178 yards from scrimmage in the Week 2 win over the Colts. Veteran TE Travis Kelce caught nine passes for 101 yards and a touchdown.
Biggest Fallers
Los Angeles Chargers (+5000)
It just keeps getting worse for the Chargers. In two weeks, they've gone from +1800 to +2500 to +5000 to win the Super Bowl. They are the second team in the Super Bowl era (since 1966) to be favored by at least 6.5 points in each of their first two games and lose both.
Their offense looks disjointed. QB Justin Herbert was picked off twice and fumbled three times in their Week 2 loss to the Raiders. They've been outscored 56-28 in their two losses.
It won't get any easier for LA's AFC squad. Their next seven games are against the Bills, Seahawks, Broncos, Chiefs, Rams, Texans, and Ravens.
Chicago Bears (+4000)
The warm feeling that blew into the Windy City following their 50+ point Week 1 dismantling of the Panthers crumbled when QB Caleb Williams crumpled to the ground in their Week 2 loss to the Vikings. Without their ace QB, the Bears were held to a field goal. Williams (hamstring) is listed as week-to-week.
Backup QB Tyson Bagent is in concussion protocol, meaning journeyman veteran Case Keenum is expected to be under center this week on MNF against the Eagles. Chicago's Super Bowl futures betting line skyrocketed from +2200 to +4000.
Houston Texans (+2200)
Is history repeating itself for the 0-2 Texans? Last season, the Texans opened the NFL season 0-3. They were 3-5, and then rattled off nine successive victories to claim the AFC South Division title.
Houston's Super Bowl odds lengthened from +2000 to +2200, but don't blame QB CJ Stroud. His 627 passing yards are the third-most in the NFL. Still, that only resulted in a pair of TD passes. The Texans never found the end zone in Week 2, losing 20-6 to the Bengals.
Best value left on the board
Jacksonville Jaguars (+2200)
The Jaguars are the only AFC South team with a win so far this season. Jacksonville's Super Bowl odds shortened from +2500 to +2200 despite a 20-13 Week 2 loss to the Denver Broncos.
It all seems to come down to whether the Jaguars' offensive line can give QB Trevor Lawrence time to work. He completes nearly 77% of his passes when he has time to throw. Under defensive pass rush pressure, the number plummets to less than 39%.
Minnesota Vikings (+3000)
The Vikings have already won two games against NFC North opponents, beating the Green Bay Packers and Chicago Bears. Minnesota's Super Bowl odds shortened from +5000 to +4500 and now to +3000 over the past two months. Even with backup Carson Wentz replacing the concussed Kyler Murray at QB, Minnesota is unbeaten.
The Vikings are doing it thanks to a defense and special teams that both rank within the top 10 in the NFL. The rushing game is mid-pack. However, Wentz is 22nd in QBR (52.0) and 29th in completion percentage (58%).
NFL previous news updates
- [September 2026]: Despite a devastating Week 1 loss, the Los Angeles Rams remain the betting favorite to win the Super Bowl
- [September 2026]: The Super Bowl odds on the Los Angeles Rams shorten again; Should you bet on a first-time Super Bowl winner?
- [August 2026]: The Los Angeles Rams and Seattle Seahawks are the only NFC teams among the top nine in Super Bowl futures markets.
- [July 2026]: NFL training camps are in full swing, and the preseason games will soon be getting underway.
- [June 2026]: Patrick Mahomes has signed a historic extension with the Kansas City Chiefs.
- [June 2026]: The Los Angeles Rams are the early-season favourites to win Super Bowl LXI.
- [May 2026]: The Atlanta Falcons have emerged as one of the league’s most talked-about teams following an aggressive offseason, and their Monday Night Football clash with the Los Angeles Rams is already generating a buzz.
- [April 2026]: The NFL Draft wrapped up, and betting boards reacted quickly. Teams that added impact talent across all seven rounds saw their futures adjust, while additional free-agent moves continued to influence the market.
- [March 2026]: Trade activity across the NFL began moving the odds, with several major player deals creating immediate changes in division races and Super Bowl pricing.
- [March 2026]: Free agency had a major effect on futures markets, as teams that landed top quarterbacks or key defensive stars saw their odds improve sharply, in some cases moving from around +2000 to +1200.
- [February 2026]: Super Bowl LX brought the market to a close, with the Seattle Seahawks beating the New England Patriots 29–13 and Kenneth Walker earning Super Bowl MVP.
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