• What: MLS Friday Night
  • Who: Inter Miami vs Nashville SC
  • When: Friday, October 24, 2025
  • Where: Chase Stadium - Miami, Florida
  • Watch: Apple TV

It's MLS Playoff Time in Major League Soccer, and already, the soccer has featured a lot of unexpected twists and turns. The good news is we have the entire second season. MLS Friday Best Bets loom large this time of year as the teams battle for the MLS Cup.

Oddsmakers are setting Inter Miami as -200 home favorites. Nashville SC is firm as the +400 road underdogs in the soccer odds.

Let us examine all the latest soccer betting lines for this match. Remember, these odds are inevitably subject to change and will change.

MLS FridayBovadaBetOnlineMyBookie
Inter Miami-200-210-205
Nashville SC+400+420+410
Draw+380+385+385

In this article, OSB gives this match a proper preview, predicts the winner of the matchup, and provides additional notes and some options on some second season betting plus soccer picks.

Best MLS Friday Betting Tips

Yes, it is essential to follow all the hottest soccer action with our MLS Online Betting Guide. Whether you are a beginner or a seasoned pro, our soccer online betting page is full of the latest betting tips, promos, apps, and much more.

Major League Soccer is a competition that heats up a little different now, Thanks to your phones, tablets, and mobile devices, you will always have the ability to place your MLS bets knowing they will go thru. Always use the best mobile betting apps to place a bet from wherever you may be. MLS Friday Best Bets are up next.

Match Overview: Inter Miami vs Nashville SC

Team Outlook: Inter Miami

Inter Miami almost topped the MLS table in the Eastern Conference with 65 points. The squad from Miami came up one point short. Due to tiebreakers, they ended up as the third seed behind FC Cincinnati. That eighth draw made a difference. One extra win would have been enough for the top seed in the East.

The Miami side just happened to play Nashville to close out the regular season. Saturday night saw Inter Miami get a hat trick from Lionel Messi in a 5-2 rout. Again, the soccer boys from Southern Florida led the MLS East led the Conference in goal differential (+26). Only the Vancouver Whitecaps (+28) had scored more than they allowed.

Injuries are always key for matches like this. However, this is a case where Inter Miami just needs a healthy Messi and his surrounding talent to play well with him. When they are not in sync, it is very apparent. If the team is though, then look out! This Inter Miami squad can score goals in bunches.

Team Spotlight: Nashville SC

Nashville SC has been an interesting squad and quite a little team. Nashville wound up with a 16-12-6 regular season record and a +13 goal differential. Most of the time, they had a negative goal differential versus the top teams. Unfortunately, they are on the road this time, facing one of the most high-powered MLS squad in the to MLS Friday Best Bets.

Among those who believe in Nashville will wonder where the team that lifted the U.S. Open Cup went. Nashville closed the season with a loss but overall dropped seven of their final 10 matches. Finding their early season form will be a challenge given how Inter Miami dominated possession, scoring chances, and the overall flow of play.

MLS Friday Best Bets For Inter Miami vs Nashville SC

If you want to wager on this match ending as a draw, the odds on that choice is a whopping +385. The spread on the match is half a goal. You can try for that -200 moneyline with Arsena but there may be better options. Meanwhile, Inter Miami is a +125 bet to win by two or more goals. That is just the beginning for MLS Friday Best Bets.

The total for the match is 3.5 goals. Bet the over at -125, or go with the under at EVEN. Let us be blunt. Nashville has had all sorts of defensive issues over the final third of the season. Goalkeeping can only bail out a team for so long. If Inter Miami presses from the opening minute, Nashville SC is going to give up goals.

Something to note is that Inter Miami is a surprising -115 to lead after 45 minutes. Could Nashville SC keep this a tight game? Anything is possible but it does appear strange that the second half prop is now -130. .

Bet a correct score prop or move the spread around a little more. If you want to risk it, betting Inter Miami to win by three or more goals pays a staggering +255 on Bovada and BetOnline. An Over of 4.5 goals stands at +180 currently. Given, the home crowd and how Inter Miami plays on adrenaline, they might score five goals themselves.

Latest MLS Friday Best Bets

When it comes to MLS futures, Inter Miami is set as the +500 betting choice to win the 2025 MLS Cup. The side has been the favorite since the season started. Vancouver, San Diego, and Philadelphia are all lurking while LAFC is not too far off either at +750.

The start of the playoffs sometimes features upsets. Messi and company know what is at stake. If one wanted to go for a complete whitewash, Inter Miami to win by four goals or more is +550 while three goals is now at +500. Inter Miami to score four or more goals is +220. Five goals now stands at +450.   

Best Bet To Win On MLS Playoff Friday

The Inter Miami side has greater than a two thirds chance to win. It is a team that scored a whopping 81 goals during the regular season and could have had more. Take Inter Miami to win by at least two goals at +125.

Inter Miami To beat Nashville SC by two or more goals
Bovada
+125
Bet Now!

Good luck and enjoy the playoffs!