Messi to lead Inter Miami to victory over Cincinnati in Conference Semifinals

Steve Starr
By , Updated on: Nov 19, 2025 12:00 AM
FC Cincinnati vs Inter Miami Picks
  • What: Inter Miami at FC Cincinnati- Game 1
  • Where: TQL Stadium
  • When: Sunday, November 23rd at 5:00 pm EST

FC Cincinnati will host Inter Miami in the Eastern Conference Semifinals battle featuring two of Major League Soccer's biggest stars. Lionel Messi led his club to a 2-1 series victory over Nashville SC while Evander helped his team advance past Columbus 2-1 in their best-of-3 series.

Let's look at the latest betting lines for FC Cincinnati vs Inter Miami. Odds are subject to change.

BovadaSpreadMoney LineTotal Points
FC Cincinnati0 +0.5 (-120)+178Ov 3 3.5 (-112)
Inter Miami0 -0.5 (EVEN)+126Un 3 3.5 (-108)
Draw+280

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FC Cincinnati vs Inter Miami

Inter Miami (+126) is a slight road favorite over FC Cincinnati (+178) in their single-elimination Conference Semifinals matchup on Sunday. This could be Lionel Messi's last and best chance at winning an MLS Cup as both he and Luis Suarez are 38 years old, and his longtime teammates Sergio Busquets (37) and Jordi Alba (36) have already announced they'll retire after the season.

The OVER/UNDER is set at 3, 3.5 total goals. Miami scored 81 goals in 34 regular-season games. While that's 13 more than anyone else in the league, Cincinnati held Miami scoreless in both meetings this season.

Cincinnati defense

FC Cincinnati defeated Miami 3-0 in TQL Stadium on July 16 and played them to a 0-0 draw ten days later in Fort Lauderdale. While Messi missed the second game, he was bottled up in the first contest by a young and athletic Cincy club.

The Orange and Blue will try to make it a low-scoring affair as they have won eight games by 1-0 scores and seven by 2-1 counts. Of their 20 victories, 16 were by a single goal. FCC is 20-1-3 in MLS play when they score first, including the playoffs.

Messi vs Evander

Lionel Messi will soon become the first player to capture back-to-back MLS MVP awards after notching 48 goal contributions this year. Only he and San Diego FC's Anders Dreyer had more combined goals and assists than Evander, who posted his second consecutive season with 30+ goal contributions.

Still, FCC will want to avoid a run-and-gun affair as they're just 3-6-2 when they allow two or more goals. Meanwhile, the Herons have scored three or more in nine of their last 11 matches, including the postseason.

FC Cincinnati vs Inter Miami Picks

Rest could prove to be the definitive factor in the Eastern Conference Semifinals. While FC Cincinnati outscored their opponents 4-0 in their two regular season meetings, the Herons played 55 games across all competitions this year compared to Cincy's 44.

With 15 days of rest heading into Sunday's playoff showdown, we like Inter Miami to win (+126) with the OVER 3, 3.5 (-112) as Lionel Messi adds yet another chapter to his storybook career.

Inter Miami to defeat Cincinatti
Bodog
+126

Meet the author

Steve Starr

Accomplished Sports Betting Specialist with over two decades of experience in sports analytics, strategic betting formulation, and risk management, with a particular focus on professional sports such as the NFL, NBA, and NHL. Proven success in applying statistical mo...

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