The top soccer league in Italia is finally back! For a full preview of the new Serie A season, plus our expert-level predictions, you’re going to want to keep reading! There’s money to be made by following our advice so don’t go anywhere just yet!

Best Bet To Win Serie A Championship

We begin with this all-important bet on who will be the 2026 Serie champion. These odds are live at the best betting sites for soccer and as it stands, these are your betting favorites:

ClubBovadaBetUSMyBookie
Napoli+150+150+150
Inter Milan+300+300+300
Juventus+500+500+500
AC Milan+700+700+700
Roma+1000+1000+1000

No real surprises here. All the usual suspects — AC Milan, Inter Milan, Juventus, and Napoli — are atop the list. Mind you, the odds you see above will swing wildly throughout the season. Every result, injury, or even team drama will influence the betting odds. Heck, we’ve already seen that play out this preseason to Napoli.

Napoli captured its fourth Serie A title a year ago with a stunning triumph. However, its defense is already off to a bad start thanks to an injury to Romelu Lukaku. It’s not a small injury either. The star striker is expected to miss months of the season due to the thigh injury sustained during preseason. If not for the loss, we’d argue Napoli is better off this season than last.

The club had a standout summer, essentially improving at every position. The star addition? Lukaku’s Belgium teammate, Kevin De Bruyne. Even at 34 years old, De Bruyne is still one of the best midfielders in the sport. The ex-Man City player instantly makes the Napoli attack more dangerous with his wondrous passing ability.

We fully expect Napoli to win a second straight title, which mind you, has not been easy in Serie A. Matter of fact, no team has done so in six years. We’re betting that changes, though. Manager Antonio Conte has a top-flight roster that could make noise not just in Serie A, but the Champions League too. They’re that damn good.

Napoli to win 2026 Serie A title
BetUS
+150
Bet Now!

Best Bet To Finish Top 4 In Serie A

Alright, the betting odds for this bet line up pretty evenly with the championship lines. But of course, the odds are more “juiced” since there will be four winners here, not just one. Here’s how the current soccer odds shake out:

With this bet, we’re going to out on a limb and tell you which of the betting favorites you should skip. Yes, the one NOT to bet on.

That would be AC Milan, who have the fourth-best odds. It was an absolutely disastrous 2024-25 season for AC, finishing eighth in the table and missing out on Europa entirely. The lackluster result got not one, but two managers sacked in short order — first Paulo Fonseca, then Sergio Conceicao.

It was a chaotic season, but to bring in order, AC Milan looked toward the past. First, they brought back Massimiliano Allegri to manage. He was the boss a decade ago, before jumping over to Juventus. On the player side, AC Milan signed longtime Real Madrid star, Luka Modric, who turns 40 years old next month.

We don’t know about you, but neither addition gives us a whole lot of confidence. Not immediately, at least. It will take more time and youth to revive AC Milan so we expect them to finish middle of the table again, missing out on Europa in the process.

Therefore, with this bet, you can safely put money on the likes of Napoli, Juventus, and Inter. We’d be stunned if any of the three fall out of the top-4. Put the three teams into a parlay if you really want to up the payout potential too.

Best Bet To Be Relegated In Serie A

Here again, multiple bets can pan out. At the end of the season, the bottom-3 teams will all be relegated. As it stands, these clubs are most expected to get the boot:

ClubBovadaBetUSMyBookie
Pisa-150-150-150
Verona+100+100+100
Cremonese+110+110+110
Sassuolo+150+150+150
Lecce+225+225+225

With this wager, you almost always want to start with the teams that just got promoted. This season, that would be Sassuolo, Pisa, and Cremonese. The steep jump in competition is never easy — whether it’s Serie A or EPL or La Liga — so we would recommend throwing money on each of ‘em.

If you want another safe pick, try Lecce. They’ve been on the brink of relegation for multiple years now — they survived a year ago by a meager 3 points. But what’s that saying, “fly too close to the sun and you’ll get burnt”? That’d be Lecce right now.

How To Bet On Serie A This Season?

Serie A bets are abundant this season. Not just the futures bets we covered, but the weekly match bets too. Moneylines, goal over/unders, props — it’s all there for the taking over the next nine months. If you want them all in one spot, head to one of the bookmakers below.

Better yet, these same bookies offer lucrative sportsbook bonuses. Hundreds to thousands of dollars in free play could be had off these deals. That’s free money to spend as you’d like so get in on it. The table below lists our favorite offers so start there.