UEFA Champions League Picks / 12-9-2026 / Online Sports Betting

What: UEFA Champions League Matchday 6
Who: Real Madrid vs Manchester City
When: Wednesday, December 10, 2025, 3 p.m. ET
Where: Estadio Bernabeu
Watch: Paramount+/TUDN, 3:00 pm ET

The club with the most overall titles in the competition is playing host to English powerhouse Manchester City in Matchday 6 of the UEFA Champions League competition. Real Madrid, second in Spain's La Liga, is home to the perennial English Premier League contenders. Manchester City is currently second in the EPL table.

Oddsmakers are setting the home side as slight +148 favorites. You will get a +156 underdog betting line if you opt to go with Manchester City in the soccer odds.

Let’s look at the latest soccer betting lines for this match. Remember, the odds are always subject to change.

UEFA Champions League Matchday 6 Odds	The Pick
Real Madrid vs Manchester City	Man City	+156	+156	+154

In this article, OSB will review the match, predict the winner of the matchup, and provide additional notes and information on soccer picks and betting.

Best UEFA Champions League Betting Tips

Keep on top of the latest betting updates on UCL action by checking in with our UEFA Champions League page. If you're new to wagering on soccer, our soccer betting page is chock full of the best wagering advice and handy betting tips.

The UEFA Champions League is a months-long competition, but thanks to your mobile device, you'll never be more than moments away from placing your UCL wagers. Take advantage of the top mobile betting apps to place a bet wherever you might be in the course of your day.

Match Overview: Real Madrid vs Manchester City

Real Madrid has won a record 15 UCL titles. They won the first five titles from 1956 through 1960. Real Madrid's most recent win came in 2024.

Manchester City won the UEFA Champions League title in 2023. They also played in the 2021 final, losing to fellow English side Chelsea.

There's been little to choose between the two sides in previous head-to-head meetings. Man City has five wins, while Real Madrid has won four matches. Five meetings ended in draws.

Team Spotlight: Real Madrid

More than just three points for a victory may be riding on Real Madrid in this match. Rumors suggest that a loss to Man City will cost Real Madrid manager Xabi Alonso his job. His squad is just 2-2-3 over the past seven matches.

Making matters worse, defender Eder Militao will be out for four months with a serious hamstring injury

Team Spotlight: Manchester City

England international Phil Foden is carrying the hot touch for City. He's scored five goals in the past three matches. Combined with Norwegian international striker Erling Haaland, they could give fits to Real Madrid's injury-depleted defense.

Man City will be without injured midfielders Rodri (thigh) and Mateo Kovacic (ankle).

Best Real Madrid vs Manchester City Prop Bets

If you want to wager that the match will end in a draw, you'll get a line of +297 in the soccer betting odds. The match ending in a 1-1 draw is the +700 favorite in a correct score soccer prop.

Total goals for the match are set at 3.25. Bet the over at a soccer betting line of -102. Go with the under at odds of -118. Real Madrid has gone under that total in each of the club's past three matches. However, their last UCL match was a 4-3 win over Olympiacos. Manchester City hit the over in two of the past three matches.

They meet again 😤#UCL pic.twitter.com/pkWvfVNolf

— UEFA Champions League (@ChampionsLeague) December 8, 2025

Odds that both teams will be scoring are set at -225. Real Madrid is given -125 odds to be awarded more corners during the match. It's +350 that the Spanish side will post a clean sheet. Manchester City is getting a soccer betting line of +375 to be posting a clean sheet. Oddsmakers are setting Man City at +450 to record a shutout victory.

Real Madrid's Kylian Mbappe is getting soccer betting odds of +350 to score a goal during the match. The soccer betting line is set at +375 that Manchester City's Erling Haaland will find the back of the net.

Latest UEFA Champions League Futures

Oddsmakers are giving the record 15-time champs, Real Madrid, a betting line of +800 to win the UEFA Champions League in soccer futures betting. That's the same betting line that Manchester City is receiving in the soccer odds to win the UCL.

State of play: Arsenal first into knockout phase; nobody else through or out 😮#UCL pic.twitter.com/XOn6IES8HS

— UEFA Champions League (@ChampionsLeague) December 8, 2025

Current English Premier League leaders Arsenal are the chalk in this betting market at odds of +330. German super side Bayern Munich is next in this betting market at odds of +500.

The defending champions from PSG are set as the +600 third betting choice to win the 2025-26 UEFA Champions League title. Spanish La Liga leaders Barcelona, a five-time UCL winner, is given odds of +900 to be the winner of this season's title.

Best Bet To Win On UEFA Champions League Matchday 6

Winning at Real Madrid is never an easy task. In seven prior tries, Manchester City is 1-4-2 at Estadio Bernabeu.

Manchester City To win at Real Madrid

+156

Bet Now!

The timing seems right, though. Man City has won three in a row, scoring 11 goals in the process. Meanwhile, Real Madrid has two wins in the past seven matches and is coming off a 2-0 home loss to Celta Vigo. Go with the upset and take Manchester City in the UEFA Champions League picks.