NFL NFC Championship Picks: Can the San Francisco 49ers Keep Up with the Philadelphia Eagles?

NFL NFC Championship Picks: Can the San Francisco 49ers Keep Up with the Philadelphia Eagles?

Are you ready for an epic NFL NFC Championship battle between the San Francisco 49ers and the Philadelphia Eagles? We sure are. Even better, we're ultra-confident in this year's NFL NFC Championship picks, which you can find just below!

Let's start things off by looking at the latest NFL online betting odds for 49ers vs. Eagles, courtesy of the fine folks over at BetUS:

FavoriteBetUSBetUSUnderdog
Philadelphia Eagles-146+124San Francisco 49ers

Please remember to double-check these online NFL betting odds until you actually make your NFL NFC Championship predictions. Our odds for Eagles vs. 49ers are accurate entering Tuesday, January 24. That gives bookmakers plenty of time to make line adjustments before opening kick-off on Sunday, January 22, at 3 p.m. EST.

Staying current with the latest online betting odds for NFL conference championships will be a breeze if you're taking your business to the right sportsbook. And that means it's a great time of year to pillage through our reviews of the top online sportsbooks. We have pored over every detail of the user experience, so you can find the best online betting sites for the NFL playoffs without much legwork at all.

As for the NFC Championship tilt at hand, many saw this matchup coming around the middle of the season. The Eagles were dominating, and the 49ers, despite injuries to multiple quarterbacks, were spitting fire on defense and acquired superstar running back Christian McCaffrey from the Carolina Panthers. Typically, we would expect the betting lines for San Francisco vs. Philadelphia to be tighter. But as you can see above, linemakers are heavily favoring the Eagles to beat the 49ers.

Are the NFL NFC Championship betting odds reading too much into what happened last week, when Philadelphia trucked the New York Giants and San Francisco's offense struggled to score on the Dallas Cowboys? Or are the Eagles really the right pick to make the NFL Super Bowl? Let's find out.

Can the San Francisco 49ers Defense Slow Down the Philadelphia Eagles Offense?

Well, the Eagles sure as heck proved us wrong. We predicted they would fall to the New York Giants in the Divisional Round of the playoffs, mostly because we were concerned about the health of quarterback Jalen Hurts and how much he had struggled throwing the ball over the last few weeks of the regular season.

Suffice it to say, we look pretty stupid now. The Eagles offense annihilated the Giants last Saturday. Hurts showed no signs of playing injured and was exceptional at getting rid of the ball before New York's pass rush could reach him.

To be sure, the Niners defense is a different monster altogether. They can obliterate you from every level of the field and with a variety of coverages. Hurts and the Eagles offense will have their work cut out for them and shouldn't be able to waltz up and down the gridiron like they did against New York.

Still, with their steady stream of Miles Sanders ground attacks behind a sturdy offensive line, Philadelphia should be able to generate enough diversity in their play-calling to keep San Francisco on their toes. More than that, the Eagles deploy hellacious defensive schemes of their own. Few teams, in fact, are better at disrupting the pass. Philadelphia ranks first in net yards allowed per passing attempt and fifth in total interceptions and is among the best at generating sacks.

This is potentially terrible news for a Niners offense that will be starting third-string rookie quarterback Brock Purdy. Though he has fared admirably since taking the reins, his limitations were on full display against the Cowboys. San Francisco was more compelled to rely on the run game and try controlling the clock. That same conservative approach won't work against the Eagles.

OSB Prediction: Philadelphia Eagles (-146)

Philadelphia Eagles To beat the San Francisco 49ers
-146
BetUS

The Eagles Point Spread Offers Better Value Than They're NFL NFC Championship Moneyline

Below you can see the latest NFL point spread betting odds for the NFC Championship game between the Niners and Eagles:

  • Philadelphia Eagles, -2.5 (-120)
  • San Francisco 49ers, +2.5 (-102)

Winning by more than a field goal is sort of the Eagles' specialty. Only one of their 15 total victories so far has come by fewer than three points. 

Granted, the Niners might be the best team Philly has faced this year. But San Francisco's offense is prone to lulls the Eagles offense has never really experienced. 

If we thought Philly would struggle to move the ball, the Niners spread would be more intriguing. Instead, it's a hard pass for us.

OSB Prediction: Philadelphia Eagles, -2.5 (-120)

Philadelphia Eagles To cover the point spread against the San Francisco 49ers
-120
BetUS

Good Luck Betting the Over/Under in Eagles vs. 49ers

Here are the latest NFL over/under betting odds for the NFC Championship game between the Eagles and Niners:

  • Over 45.5 (-115)
  • Under 45.5 (-105)

This is what we call a well-placed line—one that makes both the over and under look extremely attractive.

And when push comes to shove, we're inclined to go with the under.

San Francisco's playoff offense looks light on big-play potential. Dallas' defense is okay, but Philly's way better, and the Niners mustered just 19 total points against the latter. And though the Eagles offense has the capacity to shift this entire line towards the over on their own, we have to credit San Francisco's high-pressure and extremely disciplined defense for allowing opponents to top 25 points just three times all year.

OSB Prediction: Under 45.5 (-105)

Eagles and 49ers To score under 45.5 points combined
-105
BetUS

Take a look at this list of the top online sportsbooks so you can decide which one to use for all of your NFL betting:

Meet the author

Dan Favale

Dan is a sports betting writer who can tackle any topic from presidential elections to changes in the sports betting legislation federally and on the state level. He also writes picks for NFL.